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Hobbs and Duncan win $3.9M NIAID grant to study a meningitis vaccine’s effect on gonorrhea

August 26, 2021

The NIH’s National Institute of Allergy and Infectious Diseases has awarded UNC’s Marcia Hobbs and Alex Duncan a five-year, $3.9 million grant to study how a vaccine recently developed to prevent life-threatening infections caused by group B Neisseria meningitidis, the MenB vaccine, may also protect people from infection with Neisseria gonorrhoeae, a sexually transmitted bacterial … Continued

Study from DRC shows mother-infant HBV treatment, prevention feasible

August 23, 2021

Hepatitis B virus (HBV) remains endemic throughout sub-Saharan Africa despite the widespread availability of effective childhood vaccines. In the Democratic Republic of the Congo, HBV treatment and birth-dose vaccination programs are not established. UNC School of Medicine researchers led a study to evaluate the feasibility and acceptability of HBV testing and treatment of pregnant women, … Continued

NIH awards HIV Cure Center $26.2 million over next 5 years

August 23, 2021

The National Institutes of Health has awarded approximately $53 million in annual funding over the next five years to 10 research organizations in a continued effort to find a cure for HIV. The new awards for the Martin Delaney Collaboratories for HIV Cure Research program, initiated in 2011, further expand the initiative’s 2016 renewal from six institutions to … Continued

Baric elected to National Academy of Sciences

May 9, 2021

Ralph S Baric, UNC’s William R. Kenan Jr. Distinguished Professor of Epidemiology and professor of microbiology and immunology, was one of four UNC-Chapel Hill faculty members elected as part of a class of 120 new members to the National Academy of Sciences. The honor recognizes a member’s distinguished and continuing achievements in original research. Baric … Continued

Ciccone wins clinical research award from ASTMH

November 19, 2020

Research looks at leveraging diagnostic technology to improve management of pediatric infections in low-resource settings Emily Ciccone, MD, MHS, a UNC clinical instructor and infectious diseases fellow, recently won first prize in the clinical research award session of the 2020 annual meeting of the American Society of Tropical Medicine and Hygiene. The award recognizes excellence … Continued

HIV Cure Center, Cell Microsystems to further develop single-cell diagnostic assay

October 12, 2020

Cell Microsystems and UNC’s HIV Cure Center will continue their work on developing an automated assay that can measure single cells for latent HIV, thanks to a two-year, $1.65 million contract from the National Institutes of Health. The new contract, a highly competitive phase II Small Business Innovation Research award, affirms the partners’ success resulting … Continued

African American women perceive systemic barriers to accessing HIV prevention care

September 20, 2020

Black women in the southern United States are less likely to seek HIV prevention and treatment services because they don’t trust the health care system, according to a study in the September/October issue of The Journal of the Association of Nurses in AIDS Care (JANAC) by Schenita Randolph, PhD, MPH, at Duke University School of Nursing. … Continued

Convalescent plasma clinical trial ramps up

September 7, 2020

On the heels of FDA authorization of convalescent plasma as a treatment for COVID-19, UNC researchers are conducting a clinical trial to determine the safety and efficacy of plasma that includes a higher amount of neutralizing antibodies against SARS-CoV-2. The new Coronavirus-inactivating Plasma (CoVIP) research clinical trial is designed to determine the safety and efficacy … Continued

Wohl launches clinical trial, one of 25 sites nationally testing COVID-19 treatments

September 1, 2020

  UNC Institute for Global Health and Infectious Diseases researchers have begun phase 2 and phase 3 evaluations of promising treatments for COVID-19. The UNC School of Medicine joins more than 25 initial sites participating in the clinical trials through ACTIV-2, a public-private partnership sponsored by the NIH’s National Institute of Allergy and Infectious Diseases … Continued

UNC-led consortium to study HIV-related cancers in sub-Saharan Africa

August 24, 2020

A team of UNC researchers are partnering with colleagues at four institutions in Africa to study HIV-associated malignancies. With a five-year, $6 million grant from the NIH’s National Cancer Institute, the research consortium will look at screening and diagnosing innovations for three cancers common to people with HIV: Kaposi sarcoma, cervical cancer and lymphoma. Leading … Continued

NIH awards Cohen, FHI $9.2 million for development of COVID prevention studies

July 21, 2020

The National Institutes of Health has awarded Myron Cohen, MD, director of UNC’s Institute for Global Health and Infectious Diseases, and FHI 360 $9.2 million to support research through the new COVID Prevention Network (CoVPN). The National Institute of Allergy and Infectious Diseases at the National Institutes of Health has formed the network to better … Continued

Institute research sampling, 2018-2020

July 7, 2020

By the spring of 2020, the urgency of the COVID-19 pandemic caused many researchers affiliated with UNC’s Institute for Global Health and Infectious Diseases to pivot their studies to focus on testing, treatment and prevention of the SARS-CoV-2 virus. Here, a look at some of the projects underway in the last two years.   Development … Continued

Parr, medical students conduct first study of tocilizumab in treating COVID-19

May 19, 2020

  In the first COVID-19 case series of tocilizumab in the United States, UNC-Chapel Hill researchers report sobering results. They say the drug should be used judiciously until randomized clinical trials determine tocilizumab’s true efficacy. Meanwhile, medical students sidelined from clinical rotations by the virus conducted the research with lightning speed, all virtually. In the … Continued

Study finds three strains of resistant bacteria, identifying greater diversity

May 14, 2020

    A new study by the Multi-Drug-Resistant Organism Network of the Antibacterial Resistance Leadership Group (ARLG) has found that strains of carbapenem-resistant enterobacterales (CRE), a major threat to vulnerable patient populations, are more diverse than previously thought. The MDRO Network is led by UNC Infectious Diseases investigator David van Duin, MD, PhD. Analyzing patient … Continued

Schranz receives NIH grant to study patient care for drug-use related heart infections

May 6, 2020

Asher Schranz, MD, MPH, assistant professor of medicine in the division of infectious diseases, has received a grant from the NIH National Institute on Drug Abuse for the project “Drug-use associated infective endocarditis: Post-hospitalization outcomes and patient treatment preferences.” Schranz’s research is broadly focused on the intersection of infectious diseases and substance use disorders. He … Continued

Pay-it-forward model increases STI testing and community health

April 27, 2020

Watch animation video explaining UNC Project-China’s STI pay-it-forward study. Gonorrhea and chlamydia are two common sexually transmitted infections (STIs) that increase HIV risk among many key populations, including gay and bisexual men. But most men are not tested for STIs, in part because of the cost and low community engagement. A new study from researchers … Continued

Study addresses COVID-19 infection rates for household members

April 24, 2020

By Alyssa LaFaro As seven states now require masks and face coverings for visiting essential businesses or using public transportation, it seems like those spaces are where we are most at risk for COVID-19 infection. But, in truth, the riskiest place could be our homes — at least, if you live with someone who tests positive for the … Continued