Convalescent plasma clinical trial ramps up

September 7, 2020

On the heels of FDA authorization of convalescent plasma as a treatment for COVID-19, UNC researchers are conducting a clinical trial to determine the safety and efficacy of plasma that includes a higher amount of neutralizing antibodies against SARS-CoV-2. The new Coronavirus-inactivating Plasma (CoVIP) research clinical trial is designed to determine the safety and efficacy … Continued

Wohl launches clinical trial, one of 25 sites nationally testing COVID-19 treatments

September 1, 2020

  UNC Institute for Global Health and Infectious Diseases researchers have begun phase 2 and phase 3 evaluations of promising treatments for COVID-19. The UNC School of Medicine joins more than 25 initial sites participating in the clinical trials through ACTIV-2, a public-private partnership sponsored by the NIH’s National Institute of Allergy and Infectious Diseases … Continued

UNC-led consortium to study HIV-related cancers in sub-Saharan Africa

August 24, 2020

A team of UNC researchers are partnering with colleagues at four institutions in Africa to study HIV-associated malignancies. With a five-year, $6 million grant from the NIH’s National Cancer Institute, the research consortium will look at screening and diagnosing innovations for three cancers common to people with HIV: Kaposi sarcoma, cervical cancer and lymphoma. Leading … Continued

NIH awards Cohen, FHI $9.2 million for development of COVID prevention studies

July 21, 2020

The National Institutes of Health has awarded Myron Cohen, MD, director of UNC’s Institute for Global Health and Infectious Diseases, and FHI 360 $9.2 million to support research through the new COVID Prevention Network (CoVPN). The National Institute of Allergy and Infectious Diseases at the National Institutes of Health has formed the network to better … Continued

Institute research sampling, 2018-2020

July 7, 2020

By the spring of 2020, the urgency of the COVID-19 pandemic caused many researchers affiliated with UNC’s Institute for Global Health and Infectious Diseases to pivot their studies to focus on testing, treatment and prevention of the SARS-CoV-2 virus. Here, a look at some of the projects underway in the last two years.   Development … Continued

Parr, medical students conduct first study of tocilizumab in treating COVID-19

May 19, 2020

  In the first COVID-19 case series of tocilizumab in the United States, UNC-Chapel Hill researchers report sobering results. They say the drug should be used judiciously until randomized clinical trials determine tocilizumab’s true efficacy. Meanwhile, medical students sidelined from clinical rotations by the virus conducted the research with lightning speed, all virtually. In the … Continued

Study finds three strains of resistant bacteria, identifying greater diversity

May 14, 2020

    A new study by the Multi-Drug-Resistant Organism Network of the Antibacterial Resistance Leadership Group (ARLG) has found that strains of carbapenem-resistant enterobacterales (CRE), a major threat to vulnerable patient populations, are more diverse than previously thought. The MDRO Network is led by UNC Infectious Diseases investigator David van Duin, MD, PhD. Analyzing patient … Continued

Schranz receives NIH grant to study patient care for drug-use related heart infections

May 6, 2020

Asher Schranz, MD, MPH, assistant professor of medicine in the division of infectious diseases, has received a grant from the NIH National Institute on Drug Abuse for the project “Drug-use associated infective endocarditis: Post-hospitalization outcomes and patient treatment preferences.” Schranz’s research is broadly focused on the intersection of infectious diseases and substance use disorders. He … Continued

Pay-it-forward model increases STI testing and community health

April 27, 2020

Watch animation video explaining UNC Project-China’s STI pay-it-forward study. Gonorrhea and chlamydia are two common sexually transmitted infections (STIs) that increase HIV risk among many key populations, including gay and bisexual men. But most men are not tested for STIs, in part because of the cost and low community engagement. A new study from researchers … Continued

Study addresses COVID-19 infection rates for household members

April 24, 2020

By Alyssa LaFaro As seven states now require masks and face coverings for visiting essential businesses or using public transportation, it seems like those spaces are where we are most at risk for COVID-19 infection. But, in truth, the riskiest place could be our homes — at least, if you live with someone who tests positive for the … Continued

Faculty affiliates turn focus to COVID-19 treatments, prevention research

April 6, 2020

  Researchers within UNC’s School of Medicine are working tirelessly to provide knowledge to impact the current COVID-19 pandemic and future pandemics. “UNC SOM is home to many world-renowned experts on infectious disease and virology,” says Blossom Damania, Boshamer Distinguished Professor and Vice Dean for Research at the UNC School of Medicine. “We are very … Continued

Researchers receive up to $10.7 million to study chlamydia vaccine

May 30, 2019

  Chlamydia is the most prevalent bacterial sexually transmitted infection (STI) in the world. There is no vaccine to prevent infection. However, researchers from the University of North Carolina at Chapel Hill, in partnership with colleagues at other sites in the U.S., Europe and Australia, will receive up to $10.7 million over five years from … Continued