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Antimalarial Drug Use and Practices in Uganda

August 13, 2022

“The findings of this work are critically important and more of this type of research is desperately needed in Africa. Appropriate diagnostic and therapeutic stewardship is essential for both improving the clinical care of people and for the long term protection of these interventions from resistance resulting in treatment failure.” Jon Juliano In the remote … Continued

I AM IGHID: Joelle Howard

August 12, 2022

Regulatory Affairs (RA) plays a critical role throughout the grant lifecycle, ensuring protocol integrity in the development of drugs and vaccines on the path to human use. Joelle Howard, who goes by Jo, joined IGHID last June. She is one of three regulatory document specialists who work across departments, schools, and countries to maintain accurate … Continued

Investigators Discuss Their Research As New Fiscal Year Begins

August 12, 2022

Global health research is a collaborative process, and each researcher at the Institute for Global Health & Infectious Diseases contributes a piece to solving the puzzle of disease and morbidity. With a new fiscal year underway, read what some of our investigators are working on to improve the health of global populations. Their multi-disciplinary findings will be … Continued

Addressing Racism’s Role in the US HIV Epidemic: Qualitative Findings from Three “Ending the HIV Epidemic” Prevention Projects

August 8, 2022

Researchers from the Institute for Global Health and Infectious Diseases, the Gillings School of Global Public Health, and Center for Health Equity Research reviewed qualitative data from three “Ending the HIV Epidemic” (EHE) projects, published in the July issue of Journal of Acquired Immune Deficiency Syndrome (JAIDS). In the article, Kate Muessig, PhD, associate professor … Continued

Scientists Create Long-acting Injectable Drug Delivery System for Tuberculosis

August 8, 2022

Led by Martina Kovarova, PhD, Miriam Braunstein, PhD, and J. Victor Garcia, PhD, UNC School of Medicine researchers showed in vivo efficacy of a long-acting injectable formulation of the anti-TB drug rifabutin. In 2020, more than 1.5 million people around the world died of tuberculosis, marking the first time in more than a decade that … Continued

Sustained Efficacy of Long-Acting Cabotegravir for PrEP Among Cisgender Women – Findings from HPTN 084 Study

August 1, 2022

Researchers from the HIV Prevention Trials Network (HPTN) presented updated results from the HPTN 084 long-acting cabotegravir (CAB) for pre-exposure prophylaxis (PrEP) study at the AIDS 2022 conference in Montreal. New findings show reductions in HIV incidence were sustained in the 12 months following trial unblinding (November 5, 2020, through November 5, 2021). “HIV infection … Continued

CDC renews five-year funding for vector-borne disease threats

July 25, 2022

The Center for Disease Control and Prevention (CDC) has announced the five-year funding renewal of the Southeastern Center for Vector-Borne Diseases (SECVBD), an interdisciplinary team of researchers that includes UNC’s Ross Boyce, MD, MSc, a member of the UNC Institute for Global Health & Infectious Diseases and assistant professor in infectious diseases and epidemiology, and … Continued

Study shows the positive effect of preventative therapy for malaria is mediated by gestational weight gain, influenced by intestinal pathogens

June 24, 2022

Recently published in eBioMedicine, this study represents the work of the late Professor Steve Meshnick who served as mentor to Andreea Waltmann, a postdoctoral scholar with the Institute for Global Health & Infectious Diseases. Dr. Meshnick died August 5, 2020.  Malaria in pregnancy (MiP) is a major public health problem with substantial risks for mothers and their babies. The combination … Continued

NIAID recognizes HPTN’s groundbreaking work in covid prevention tools

June 9, 2022

The 2022 HPTN Annual Meeting took place June 5-8 in Washington, D.C., bringing hundreds of worldwide researchers, collaborators, community representatives, and government health officials together to share updates and accomplishments and re-engage with each other as a community. HPTN Principal Investigators Myron Cohen, MD, director of the UNC Institute for Global Health & Infectious Diseases … Continued

Baric led center receives $65 million grant

June 8, 2022

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has awarded the UNC Gillings School of Global Public Health a $65 million grant establishing an Antiviral Drug Discovery (AViDD) Center to develop oral antivirals that can combat pandemic-level viruses like COVID-19. The center builds upon and is … Continued

Effect of intimate partner violence on oral PrEP adherence among adolescent girls and young women

June 7, 2022

Intimate partner violence events may either impede or motivate PrEP adherence among African adolescent girls and young women, with age appearing to be an important consideration for IPV-related adherence interventions, according to IGHID researchers Lisa Hightow-Weidman, MD, MPH, professor of infectious diseases and principal investigator for the UNC Behavioral and Technology Lab, and Audrey Pettifor, … Continued

Researchers evaluate diagnostic testing landscape for tick-borne disease in the Southeast

May 17, 2022

Tick-borne diseases (TBD) including Spotted Fever Group Rickettsiosis (SFGR), ehrlichiosis, and increasingly Lyme disease, represent a substantial public health concern throughout much of the Southeastern United States. North Carolina experiences some of the highest rates of SFGR and ehrlichiosis in the United States, often accounting for more than of 10% and 5% of cases reported to the … Continued

NIH Renews the UJMT Fogarty Global Health Training Partnership

May 6, 2022

The UJMT Fogarty Global Health Fellows Consortium (UJMT)–a partnership between UNC-Chapel Hill, Johns Hopkins University, Morehouse School of Medicine and Tulane University–has been renewed for the coming five years. It is one of seven groups to be funded under the new Launching Future Leaders in Global Health (LAUNCH) training initiative, supported by the Fogarty International … Continued

Youth-Focused Intervention Activity Focuses On Solutions For Promoting PrEP Awareness

April 28, 2022

Joseph Tucker, MD, PhD, MA, a member of the UNC Institute for Global Health and Infectious Diseases and associate professor in the division of infectious diseases, encourages HIV testing through his work in the US, China and South Africa. He also promotes youth-friendly HIV prevention and self-testing services. In early April, Dr. Tucker participated in … Continued

IGHID, CAC Host Visiting Scholars from China and Vietnam

April 26, 2022

Visiting scholars make important contributions to the UNC community enriching the research and educational experience for everyone. On April 13, the UNC Institute for Global Health & Infectious Diseases (IGHID) and Carolina Asia Center (CAC) hosted scholars from the Southern Medical University in Guangzhou, China, and the Hanoi Medical University in Hanoi, Vietnam. “The Global Health … Continued

STD Awareness in April: Infectious Disease Experts Are Working to Advance the Development of Vaccines for Sexually Transmitted Infections

April 20, 2022

During April, STD Awareness provides an opportunity to talk about STIs and encourage individuals to be proactive about their sexual health and promotes regular STI/HIV screening and testing. Although research in sexually transmitted infections (STIs) has evolved rapidly on multiple fronts, a critical remaining challenge is the development of safe and effective vaccines for diseases that pose … Continued

UNC Landmark Study Paves the Way for Universal Obstetric Ultrasound

April 7, 2022

Establishing accurate gestational age with ultrasound early in pregnancy is essential to delivering high-quality care.Yet, the high cost for equipment and the need for trained sonographers limits its use in low-resource settings. A new study published in NEJM Evidence introduces a novel opportunity to democratize obstetric ultrasound. UNC investigators from the Institute for Global Health … Continued