Survivors of the Ebola outbreak in 2014 report a wide range of lingering symptoms that include fatigue and muscle pain, as well as neurological issues. But not much has been known about the persistence and severity of the symptoms over time. Investigators from the Institute for Global Health & Infectious Diseases, David Wohl, MD, professor … Continued

COVID-19 has become a leading cause of death and reduced life expectancy in the U.S., especially among Black and Latino populations. David Wohl, MD, member of the Institute for Global Health & Infectious Diseases and professor of medicine in infectious diseases, and first author Jessie Edwards, PhD, assistant professor in the department of epidemiology at the … Continued

Almost 40 years after the discovery of HIV, a new NOVA program “Ending HIV in America” reflects on the history of one of the most elusive and deadly viruses to ever infect humans. Myron “Mike” Cohen, MD, director of the UNC Institute for Global Health & Infectious Diseases known for his work on transmission and … Continued

Angela Wahl, PhD, a member of the Institute for Global Health & Infectious Diseases (IGHID), the International Center for the Advancement for Translational Science, and assistant professor in the division of infectious diseases has received a $3.2 million R01 award to study the role of microglia in HIV latency and persistence in the brain. Over … Continued

In a hospital, ambulance or a remote village in sub-Saharan Africa, researchers are focused on improving pregnancy outcomes with access to high-quality obstetric ultrasound, when and where it’s needed. Each year some 300,000 women and 3 million babies worldwide die during childbirth or shortly thereafter, according to the World Health Organization, which recommends ultrasound for all pregnancies … Continued

Jonathan Juliano, MD, MPSH, Professor of Infectious Diseases and Associate Director of the Institute for Global Health and Infectious Diseases, with fellow IDEEL investigators Jessica Lin, MD, MSCR, and Jonathan Parr, MD, MPH, and co-PIs from the University of Florida (UF) and Centre Pasteur Cameroon, has received a $3.4 million R01 grant award to study … Continued

UNC-Chapel Hill has received a $17 million grant from the Bill & Melinda Gates Foundation to continue groundbreaking work in artificial intelligence (AI)-enabled obstetric ultrasound. CHAPEL HILL, NC – The new award will support an interdisciplinary team from the UNC School of Medicine and Gillings School of Global Public Health, with collaborators in Zambia, Kenya, … Continued

In the remote villages of Bugoye sub-county at the foot of Uganda’s Rwenzori Mountains a rolling landscape stretches across lush river valleys and steep hillsides. It’s the kind of terrain that might make for a beautiful and strenuous weekend hike for visitors but not necessarily for the people who live there. Residents of this region … Continued

Regulatory Affairs (RA) plays a critical role throughout the grant lifecycle, ensuring protocol integrity in the development of drugs and vaccines on the path to human use. Joelle Howard, who goes by Jo, joined IGHID last June. She is one of three regulatory document specialists who work across departments, schools, and countries to maintain accurate … Continued

Global health research is a collaborative process, and each researcher at the Institute for Global Health & Infectious Diseases contributes a piece to solving the puzzle of disease and morbidity. With a new academic year underway, read what some of our investigators are working on to improve the health of global populations. Their multi-disciplinary findings will be … Continued

Researchers from the Institute for Global Health and Infectious Diseases, the Gillings School of Global Public Health, and Center for Health Equity Research reviewed qualitative data from three “Ending the HIV Epidemic” (EHE) projects, published in the July issue of Journal of Acquired Immune Deficiency Syndrome (JAIDS). In the article, Kate Muessig, PhD, associate professor … Continued

Led by Martina Kovarova, PhD, Miriam Braunstein, PhD, and J. Victor Garcia, PhD, UNC School of Medicine researchers showed in vivo efficacy of a long-acting injectable formulation of the anti-TB drug rifabutin. In 2020, more than 1.5 million people around the world died of tuberculosis, marking the first time in more than a decade that … Continued

Researchers from the HIV Prevention Trials Network (HPTN) presented updated results from the HPTN 084 long-acting cabotegravir (CAB) for pre-exposure prophylaxis (PrEP) study at the AIDS 2022 conference in Montreal. New findings show reductions in HIV incidence were sustained in the 12 months following trial unblinding (November 5, 2020, through November 5, 2021). “HIV infection … Continued

The Center for Disease Control and Prevention (CDC) has announced the five-year funding renewal of the Southeastern Center for Vector-Borne Diseases (SECVBD), an interdisciplinary team of researchers that includes UNC’s Ross Boyce, MD, MSc, a member of the UNC Institute for Global Health & Infectious Diseases and assistant professor in infectious diseases and epidemiology, and … Continued

Recently published in eBioMedicine, this study represents the work of the late Professor Steve Meshnick who served as mentor to Andreea Waltmann, a postdoctoral scholar with the Institute for Global Health & Infectious Diseases. Dr. Meshnick died August 5, 2020.  Malaria in pregnancy (MiP) is a major public health problem with substantial risks for mothers and their babies. The combination … Continued

Infectious disease research at the UNC Institute for Global Health & Infectious Diseases (IGHID) attracts unique people driven to make big change in the world. As HIV/AIDS turned 40 in 2021, the world was immersed in a different pandemic, one that brought reminders of the tremendous change science made possible in understanding, treating and preventing … Continued

The 2022 HPTN Annual Meeting took place June 5-8 in Washington, D.C., bringing hundreds of worldwide researchers, collaborators, community representatives, and government health officials together to share updates and accomplishments and re-engage with each other as a community. HPTN Principal Investigators Myron Cohen, MD, director of the UNC Institute for Global Health & Infectious Diseases … Continued

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has awarded the UNC Gillings School of Global Public Health a $65 million grant establishing an Antiviral Drug Discovery (AViDD) Center to develop oral antivirals that can combat pandemic-level viruses like COVID-19. The center builds upon and is … Continued

Intimate partner violence events may either impede or motivate PrEP adherence among African adolescent girls and young women, with age appearing to be an important consideration for IPV-related adherence interventions, according to IGHID researchers Lisa Hightow-Weidman, MD, MPH, professor of infectious diseases and principal investigator for the UNC Behavioral and Technology Lab, and Audrey Pettifor, … Continued

In 2021, women and girls in sub-Saharan Africa accounted for three of five new HIV infections, and young women aged 15–24 years were three times as likely as young men in the same age group to be infected with HIV. Despite expanded access to oral PrEP, women are disproportionately affected by HIV experiencing considerable barriers … Continued