“The findings of this work are critically important and more of this type of research is desperately needed in Africa. Appropriate diagnostic and therapeutic stewardship is essential for both improving the clinical care of people and for the long term protection of these interventions from resistance resulting in treatment failure.” Jon Juliano In the remote … Continued

Regulatory Affairs (RA) plays a critical role throughout the grant lifecycle, ensuring protocol integrity in the development of drugs and vaccines on the path to human use. Joelle Howard, who goes by Jo, joined IGHID last June. She is one of three regulatory document specialists who work across departments, schools, and countries to maintain accurate … Continued

Global health research is a collaborative process, and each researcher at the Institute for Global Health & Infectious Diseases contributes a piece to solving the puzzle of disease and morbidity. With a new fiscal year underway, read what some of our investigators are working on to improve the health of global populations. Their multi-disciplinary findings will be … Continued

Researchers from the Institute for Global Health and Infectious Diseases, the Gillings School of Global Public Health, and Center for Health Equity Research reviewed qualitative data from three “Ending the HIV Epidemic” (EHE) projects, published in the July issue of Journal of Acquired Immune Deficiency Syndrome (JAIDS). In the article, Kate Muessig, PhD, associate professor … Continued

Led by Martina Kovarova, PhD, Miriam Braunstein, PhD, and J. Victor Garcia, PhD, UNC School of Medicine researchers showed in vivo efficacy of a long-acting injectable formulation of the anti-TB drug rifabutin. In 2020, more than 1.5 million people around the world died of tuberculosis, marking the first time in more than a decade that … Continued

Researchers from the HIV Prevention Trials Network (HPTN) presented updated results from the HPTN 084 long-acting cabotegravir (CAB) for pre-exposure prophylaxis (PrEP) study at the AIDS 2022 conference in Montreal. New findings show reductions in HIV incidence were sustained in the 12 months following trial unblinding (November 5, 2020, through November 5, 2021). “HIV infection … Continued

The Center for Disease Control and Prevention (CDC) has announced the five-year funding renewal of the Southeastern Center for Vector-Borne Diseases (SECVBD), an interdisciplinary team of researchers that includes UNC’s Ross Boyce, MD, MSc, a member of the UNC Institute for Global Health & Infectious Diseases and assistant professor in infectious diseases and epidemiology, and … Continued

Recently published in eBioMedicine, this study represents the work of the late Professor Steve Meshnick who served as mentor to Andreea Waltmann, a postdoctoral scholar with the Institute for Global Health & Infectious Diseases. Dr. Meshnick died August 5, 2020.  Malaria in pregnancy (MiP) is a major public health problem with substantial risks for mothers and their babies. The combination … Continued

Infectious disease research at the UNC Institute for Global Health & Infectious Diseases (IGHID) attracts unique people driven to make big change in the world. As HIV/AIDS turned 40 in 2021, the world was immersed in a different pandemic, one that brought reminders of the tremendous change science made possible in understanding, treating and preventing … Continued

The 2022 HPTN Annual Meeting took place June 5-8 in Washington, D.C., bringing hundreds of worldwide researchers, collaborators, community representatives, and government health officials together to share updates and accomplishments and re-engage with each other as a community. HPTN Principal Investigators Myron Cohen, MD, director of the UNC Institute for Global Health & Infectious Diseases … Continued

The National Institute of Allergy and Infectious Diseases (NIAID), part of the National Institutes of Health (NIH), has awarded the UNC Gillings School of Global Public Health a $65 million grant establishing an Antiviral Drug Discovery (AViDD) Center to develop oral antivirals that can combat pandemic-level viruses like COVID-19. The center builds upon and is … Continued

Intimate partner violence events may either impede or motivate PrEP adherence among African adolescent girls and young women, with age appearing to be an important consideration for IPV-related adherence interventions, according to IGHID researchers Lisa Hightow-Weidman, MD, MPH, professor of infectious diseases and principal investigator for the UNC Behavioral and Technology Lab, and Audrey Pettifor, … Continued

In 2021, women and girls in sub-Saharan Africa accounted for three of five new HIV infections, and young women aged 15–24 years were three times as likely as young men in the same age group to be infected with HIV. Despite expanded access to oral PrEP, women are disproportionately affected by HIV experiencing considerable barriers … Continued

Amy Loftis takes charge and takes care The Carolina Together Testing Program team got a lab up and running in an astonishing 11 weeks, making it possible for students to return to campus during the pandemic, before vaccines were widely available. For their heroic efforts in setting up and operating the COVID Surveillance Lab, Amy Loftis, … Continued

Tick-borne diseases (TBD) including Spotted Fever Group Rickettsiosis (SFGR), ehrlichiosis, and increasingly Lyme disease, represent a substantial public health concern throughout much of the Southeastern United States. North Carolina experiences some of the highest rates of SFGR and ehrlichiosis in the United States, often accounting for more than of 10% and 5% of cases reported to the … Continued

The UJMT Fogarty Global Health Fellows Consortium (UJMT)–a partnership between UNC-Chapel Hill, Johns Hopkins University, Morehouse School of Medicine and Tulane University–has been renewed for the coming five years. It is one of seven groups to be funded under the new Launching Future Leaders in Global Health (LAUNCH) training initiative, supported by the Fogarty International … Continued

Joseph Tucker, MD, PhD, MA, a member of the UNC Institute for Global Health and Infectious Diseases and associate professor in the division of infectious diseases, encourages HIV testing through his work in the US, China and South Africa. He also promotes youth-friendly HIV prevention and self-testing services. In early April, Dr. Tucker participated in … Continued

Visiting scholars make important contributions to the UNC community enriching the research and educational experience for everyone. On April 13, the UNC Institute for Global Health & Infectious Diseases (IGHID) and Carolina Asia Center (CAC) hosted scholars from the Southern Medical University in Guangzhou, China, and the Hanoi Medical University in Hanoi, Vietnam. “The Global Health … Continued

During April, STD Awareness provides an opportunity to talk about STIs and encourage individuals to be proactive about their sexual health and promotes regular STI/HIV screening and testing. Although research in sexually transmitted infections (STIs) has evolved rapidly on multiple fronts, a critical remaining challenge is the development of safe and effective vaccines for diseases that pose … Continued

Establishing accurate gestational age with ultrasound early in pregnancy is essential to delivering high-quality care.Yet, the high cost for equipment and the need for trained sonographers limits its use in low-resource settings. A new study published in NEJM Evidence introduces a novel opportunity to democratize obstetric ultrasound. UNC investigators from the Institute for Global Health … Continued