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Salvage Chemotherapy for Adults with Relapsed or Refractory Lymphoma

August 20, 2017

August 2017 – Lymphoma is highly associated with HIV in sub-Saharan Africa and contributes to worse outcomes relative to resource-rich settings. This study describes 21 patients with relapse or refractory lymphoma who were prospectively treated with salvage chemotherapy in Malawi.

Cancer Trials in sub-Saharan Africa

July 1, 2017

July 2017- Dr. Gopal proposes a potential resource-tailored framework for cancer clinical trials and for aligning care and research in SSA.

HIV-associated malignancies in sub-Saharan Africa: an overview

January 1, 2017

January, 2017 – This review highlights recent developments for HIV-associated malignancies in low and middle income countries and suggests that sustained investment within these settings can help catalyze a cancer care and research agenda that benefit patients worldwide.

Impact of loss to follow-up on pediatric lymphoma study outcome

December 13, 2016

November 2016 – Limited follow-up with incomplete retention is common among studies involving pediatric lymphoma patients in sub-Saharan Africa. This study examines the effects of retention and follow-up times on overall survival estimates.

Subtyping Sub-Saharan Esophageal Squamous Cell Carcinoma

October 6, 2016

October 2016- This study demonstrates discrete subtypes of esophageal squamous cell carcinoma (ESCC) in SSA, and suggests that the endemic nature of this disease reflects exposure to a carcinogen other than tobacco and oncogenic viruses.

Environmental Risk Factors for Oesophageal Cancer

September 29, 2015

September 2015 – Exploring environmental factors associated with oesophageal cancer in Malawi, Firewood cooking, cigarette smoking, and use of white maize flour all had strong associations with squamous cell carcinoma of the oesophagus.

High Rates of Cervical Cancer Among HIV-Infected Women in Malawi

May 21, 2015

May 2015 – Cervical cancer is the most common cancer among women in Malawi. Using pathological specimens from 630 Malawian, this study examines associations between various pathological findings and the presence of high-grade dysplasia. 

Pathologically Confirmed Breast Cancer in Malawi

March 29, 2015

March 2015 – Investigating the clinical profile of the most common female cancer in Africa, Malawian women with breast cancer were found to be young, have long symptom duration prior to diagnosis, and exhibit poorly differentiated tumors.