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Mature Outcomes and Prognostic Indices in DLBCL in Malawi

December 11, 2018

December 2018- Outcomes for diffuse large B-cell lymphoma (DLBCL) in sub-Saharan Africa are poorly described. We report mature data from one of the first prospective SSA cohorts and propose a setting-appropriate prognostic model.

HIV-Associated Multicentric Castleman Disease In Malawi

November 26, 2018

November 2018-  Despite high burden of Kaposi sarcoma and HIV, multicentric Castleman disease is rarely reported in SSA. To supplement previous reports on MCD cases in Malawi, we describe a larger cohort of MCD patients with longer follow-up.

‘Discovering’ primary effusion lymphoma in Malawi

October 1, 2018

September 2018- Although HIV and HHV8 are highly prevalent in SSA, there are scarce reports of primary effusion lymphoma (PEL) from the region, likely reflecting underdiagnosis. This article describes the two recently confirmed cases of extracavitary PEL in Malawi.  

Treating Burkitt Lymphoma in Children and AYA in Sub-Saharan Africa

July 19, 2018

July 2018- Although highly effective, high-intensity cytotoxic treatments for Burkitt lymphoma are available in resource-rich settings, these therapies are usually not feasible in SSA, and lower-intensity continuous infusion approaches are impractical. We review current treatment approaches in SSA and discuss options for risk stratification and individualize therapy.

Plasmablastic lymphoma in Malawi

June 29, 2018

June 2018- Despite high prevalence of HIV in SSA, descriptions of Plasmablastic lymphoma (PBL) are scare.  In one of the first clinical descriptions of PBL, we report on characteristics, treatment, and outcomes of 12 pathologically confirmed PBL cases in Lilongwe.

Guidelines for sub-Saharan Africa: a Call for Evidence

April 11, 2018

April 2018- Cancer care in resource-limited settings is radically different from cancer care in resource-rich settings. Drs. Painschab and Gopal comment on the urgent need for region-specific data and clinical trials to address the rising cancer burden in SSA.

Global Health: What’s in It for Us?

October 10, 2017

October 2017- In this essay, Dr. Satish Gopal addresses why he provides cancer care and conducts research in Malawi, and how global health efforts benefit the United States and human health more broadly.

Extranodal Natural Killer/T-cell Lymphoma in Malawi

September 6, 2017

September 2017- Our experience with these patients highlights that ENKTCL does indeed occur in SSA, increases familiarity with ENKTCL among clinicians and pathologists throughout the region, and emphasizes the need for better diagnosis and treatment for this neglected population.