December 2018- Outcomes for diffuse large B-cell lymphoma (DLBCL) in sub-Saharan Africa are poorly described. We report mature data from one of the first prospective SSA cohorts and propose a setting-appropriate prognostic model.
November 2018- Despite high burden of Kaposi sarcoma and HIV, multicentric Castleman disease is rarely reported in SSA. To supplement previous reports on MCD cases in Malawi, we describe a larger cohort of MCD patients with longer follow-up.
September 2018- Although HIV and HHV8 are highly prevalent in SSA, there are scarce reports of primary effusion lymphoma (PEL) from the region, likely reflecting underdiagnosis. This article describes the two recently confirmed cases of extracavitary PEL in Malawi.
July 2018- Although highly effective, high-intensity cytotoxic treatments for Burkitt lymphoma are available in resource-rich settings, these therapies are usually not feasible in SSA, and lower-intensity continuous infusion approaches are impractical. We review current treatment approaches in SSA and discuss options for risk stratification and individualize therapy.
June 2018- Despite high prevalence of HIV in SSA, descriptions of Plasmablastic lymphoma (PBL) are scare. In one of the first clinical descriptions of PBL, we report on characteristics, treatment, and outcomes of 12 pathologically confirmed PBL cases in Lilongwe.
June 2018- Efforts to translate and culturally validate patient-reported health-related quality of life measures are scarce in SSA are scarce. This study translates the PROMIS-25 to Chichewa and assesses its validity and reliability in our setting.
April 2018- Cancer care in resource-limited settings is radically different from cancer care in resource-rich settings. Drs. Painschab and Gopal comment on the urgent need for region-specific data and clinical trials to address the rising cancer burden in SSA.
March 2018- We examined risk factors and reasons for treatment abandonment among Malawian children with lymphoma, the most common pediatric cancer in SSA.
October 2017- In this essay, Dr. Satish Gopal addresses why he provides cancer care and conducts research in Malawi, and how global health efforts benefit the United States and human health more broadly.
September 2017- Our experience with these patients highlights that ENKTCL does indeed occur in SSA, increases familiarity with ENKTCL among clinicians and pathologists throughout the region, and emphasizes the need for better diagnosis and treatment for this neglected population.