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High Cancer Burden Among ART Users in Malawi

December 6, 2018

December 2018- In sub-Saharan Africa, limited epidemiological data describe cancer burden among ART users. We link cases from the population-based cancer registry with EMRs supporting ART delivery in Malawi’s two largest HIV cohorts, Lighthouse Trust and Queen Elizabeth Central Hospital to identify cancer burden.

HIV-Associated Multicentric Castleman Disease In Malawi

November 26, 2018

November 2018-  Despite high burden of Kaposi sarcoma and HIV, multicentric Castleman disease is rarely reported in SSA. To supplement previous reports on MCD cases in Malawi, we describe a larger cohort of MCD patients with longer follow-up.

Plasmablastic lymphoma in Malawi

June 29, 2018

June 2018- Despite high prevalence of HIV in SSA, descriptions of Plasmablastic lymphoma (PBL) are scare.  In one of the first clinical descriptions of PBL, we report on characteristics, treatment, and outcomes of 12 pathologically confirmed PBL cases in Lilongwe.

Frequent HIV and Young Age Among Individuals With Diverse Cancers

June 8, 2018

June 2018- We report the epidemiology of patients with cancer recorded by a hospital-based cancer registry at Kamuzu Central Hospital, the sole provider of comprehensive oncology services for half the country and location of a high-volume pathology laboratory.

Salvage Chemotherapy for Adults with Relapsed or Refractory Lymphoma

August 20, 2017

August 2017 – Lymphoma is highly associated with HIV in sub-Saharan Africa and contributes to worse outcomes relative to resource-rich settings. This study describes 21 patients with relapse or refractory lymphoma who were prospectively treated with salvage chemotherapy in Malawi.

CHOP Chemotherapy for Non-Hodgkin Lymphoma with and without HIV

March 15, 2016

March 2016 – With no previous prospective studies of aggressive non-Hodgkin lymphoma treated with CHOP in sub-Saharan Africa, results of this study suggest that CHOP can be safe, effective, and feasible for treating aggressive NHL among HIV+/- individuals in Malawi.

HIV-Associated Multicentric Castleman Disease

August 15, 2015

August 2015 – Representing the first published report of Multicentric Castleman disease in SSA, this article describes the characteristics and survival for HIV-associated Multicentric Castleman disease in Malawi.

High Rates of Cervical Cancer Among HIV-Infected Women in Malawi

May 21, 2015

May 2015 – Cervical cancer is the most common cancer among women in Malawi. Using pathological specimens from 630 Malawian, this study examines associations between various pathological findings and the presence of high-grade dysplasia. 

Multiple Subtypes of Kaposi’s Sarcoma

September 29, 2014

September 2014 – Using viral transcription profiling, this study demonstrates the existence of multiple subtypes of Kaposi Sarcoma lesions for the first time in HIV- and Kaposi Sarcoma-treatment-naive patients.