December 2018- In sub-Saharan Africa, limited epidemiological data describe cancer burden among ART users. We link cases from the population-based cancer registry with EMRs supporting ART delivery in Malawi’s two largest HIV cohorts, Lighthouse Trust and Queen Elizabeth Central Hospital to identify cancer burden.
November 2018- Despite high burden of Kaposi sarcoma and HIV, multicentric Castleman disease is rarely reported in SSA. To supplement previous reports on MCD cases in Malawi, we describe a larger cohort of MCD patients with longer follow-up.
June 2018- Despite high prevalence of HIV in SSA, descriptions of Plasmablastic lymphoma (PBL) are scare. In one of the first clinical descriptions of PBL, we report on characteristics, treatment, and outcomes of 12 pathologically confirmed PBL cases in Lilongwe.
June 2018- We report the epidemiology of patients with cancer recorded by a hospital-based cancer registry at Kamuzu Central Hospital, the sole provider of comprehensive oncology services for half the country and location of a high-volume pathology laboratory.
August 2017 – Lymphoma is highly associated with HIV in sub-Saharan Africa and contributes to worse outcomes relative to resource-rich settings. This study describes 21 patients with relapse or refractory lymphoma who were prospectively treated with salvage chemotherapy in Malawi.
March 2016 – With no previous prospective studies of aggressive non-Hodgkin lymphoma treated with CHOP in sub-Saharan Africa, results of this study suggest that CHOP can be safe, effective, and feasible for treating aggressive NHL among HIV+/- individuals in Malawi.
August 2015 – Representing the first published report of Multicentric Castleman disease in SSA, this article describes the characteristics and survival for HIV-associated Multicentric Castleman disease in Malawi.
May 2015 – Cervical cancer is the most common cancer among women in Malawi. Using pathological specimens from 630 Malawian, this study examines associations between various pathological findings and the presence of high-grade dysplasia.
UNC Lineberger Comprehensive Cancer Center and the UNC Institute for Global Health & Infectious Diseases have received a $3.7 million grant from the National Cancer Institute (NCI)
September 2014 – Using viral transcription profiling, this study demonstrates the existence of multiple subtypes of Kaposi Sarcoma lesions for the first time in HIV- and Kaposi Sarcoma-treatment-naive patients.