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Gay leading phase 3 trial of COVID-19 vaccine

July 28, 2020
In February 2020, as bits of data about the SARS-CoV-2 virus started to emerge, Cindy Gay, MD, MPH, and UNC infectious diseases colleagues began meeting to formulate a local response to the virus. They’ve met weekly ever since, resorting to Zoom calls once the university sent employees home in March....

Parr, medical students conduct first study of tocilizumab in treating COVID-19

May 19, 2020
  In the first COVID-19 case series of tocilizumab in the United States, UNC-Chapel Hill researchers report sobering results. They say the drug should be used judiciously until randomized clinical trials determine tocilizumab’s true efficacy. Meanwhile, medical students sidelined from clinical rotations by the virus conducted the research with lightning...

‘Landmark’ study finds long-acting injectable drug highly effective in preventing HIV

May 18, 2020
  Large-scale study funded by NIAID and ViiV Healthcare halted early after cabotegravir, dosed every two months, shows higher efficacy than daily oral pill.   The decades-long search for a vaccine to prevent HIV reached a new milestone as results from HPTN 083, a global large-scale study, show that the...

Study finds three strains of resistant bacteria, identifying greater diversity

May 14, 2020
    A new study by the Multi-Drug-Resistant Organism Network of the Antibacterial Resistance Leadership Group (ARLG) has found that strains of carbapenem-resistant enterobacterales (CRE), a major threat to vulnerable patient populations, are more diverse than previously thought. The MDRO Network is led by UNC Infectious Diseases investigator David van...

Schranz receives NIH grant to study patient care for drug-use related heart infections

May 6, 2020
Asher Schranz, MD, MPH, assistant professor of medicine in the division of infectious diseases, has received a grant from the NIH National Institute on Drug Abuse for the project “Drug-use associated infective endocarditis: Post-hospitalization outcomes and patient treatment preferences.” Schranz’s research is broadly focused on the intersection of infectious diseases...

Report from China: Linghua Li, MD, PhD, shares COVID-19 observations

March 21, 2020
Linghua Li, MD, PhD, is an infectious disease specialist and AIDS clinic director at Eighth People’s Hospital in Guangzhou, China. She did two years of postdoctoral training in infectious diseases at Duke University and at UNC, working with the Institute’s David Wohl, MD. Here, she reports from the frontlines on dealing with COVID-19 in Guangzhou, which...