Tag: Service

Chapel Hill, NC—A new study led by researchers at the Institute for Global Health and Infectious Diseases at the University of North Carolina School of Medicine in Chapel Hill shows an urgent need for improved detection and treatment of Lassa fever, published in The Lancet Infectious Diseases. Lassa fever–a severe...

Chapel Hill, N.C. — A Phase 2 study led by Dr. Joe Eron, a member of the UNC Institute for Global Health and Infectious Diseases, shows an investigational once‑weekly, all‑oral combination of islatravir (ISL) and lenacapavir(LEN) maintains high levels of virologic suppression through 48 weeks in adults living with HIV....

Since 2008, new HIV diagnoses in the US have been reduced by about half; however, progress is not equally distributed. In 2022, only about 65% of people diagnosed with HIV in the US—and North Carolina—were virally suppressed, falling short of the national target of 95% viral suppression. Southern states, including...

Chapel Hill, NC — Researchers with the UNC Institute for Global Health and Infectious Diseases (IGHID), in collaboration with the UNC Lineberger Comprehensive Cancer Center, and UNC Project-Malawi, found adults receiving rituximab as part of cancer treatment face a significantly higher risk of developing symptomatic malaria in an endemic region....

A UNC Vietnam team led by Vivian Go, PhD, and Bill Miller, MD, PhD, researchers with the UNC Institute for Global Health and Infectious Diseases–in collaboration with Hanoi Medical University and the Vietnam Ministry of Health–found that tailoring implementation strategies to local clinic needs significantly improved the delivery of a...

Chapel Hill, NC – New research published in JAMA Network Open highlights a critical challenge facing people living with HIV as they re-enter the community after incarceration. A Zambia study led by Michael Herce, MD, MPH, MSCR, an investigator at the UNC Institute for Global Health and Infectious Diseases—in collaboration with colleagues...

Every community has unsung heroes, and in the HIV-care community there are many. Cassandra Durham is a fierce advocate for the HIV workforce whose dedication is reshaping what it means to care for people with HIV. A personal experience supporting a friend with HIV in the early 1990s—seeing his food...

The American Society of Tropical Medicine and Hygiene’s (ASTMH) Annual Meeting, Nov. 9-13 in Toronto, Ontario, Canada, drew approximately 4,900 global health professionals from around the world. Investigators from the IDEEL Lab contributed new insights to the global conversation, drawing attention to a defining crossroads in East Africa’s malaria response....

High neighborhood deprivation is linked to both greater antimicrobial resistance and higher short‑term mortality in Enterobacterales infections. For North Carolina, the implications are clear. Tackling AMR requires not only new drugs and diagnostics but also addressing healthcare disparities that leave vulnerable populations at greater risk. Chapel Hill, NC — A...

Landmark research led by William Fischer II, MD, director of emerging pathogens for the UNC Institute for Global Health and Infectious Diseases, describes the successful delivery of advanced care to patients with Marburg virus disease during Rwanda’s third largest outbreak on record, published in The Lancet Infectious Diseasesand The New...

In a recent podcast, The Lone Star Tick & One Patient’s Experience With Ehrlichiosis, Dr. Ron Falk speaks with Dr. Ross Boyce, an expert in tick-borne illnesses, and Dr. Katherine Huffman-Falk, a retired nephrologist who was recently bitten by a tick. This podcast talks about what a tick-borne disease is...

Published today in the New England Journal of Medicine, this trial led by Ross Boyce, MD, MSc and colleagues highlights the potential impact of permethrin-treated textiles as a novel tool in the fight against malaria. Malaria remains a major cause of childhood mortality in sub-Saharan Africa, responsible for nearly 600,000...

Members of the Institute for Global Health and Infectious Diseases have an important role to play in sharing evidence-based research that can educate policymakers and support public health initiatives. Advocating for legislation can improve healthcare systems and public health, as well as advance the field of infectious diseases. Dr. Ross...

North Carolina directly benefits from the work of global health researchers working in other countries, monitoring disease and containing outbreaks. For years, Fischer and David Wohl, MD, have contained diseases like Ebola virus, Marburg virus, Lassa virus, in West Africa, setting up field treatment units during outbreak settings to isolate and effectively care...

Mental health issues such as depression, anxiety, and stress-related illnesses are ubiquitous, but their prevalence is notably high in Vietnam among people with HIV (PWH) who inject drugs. Studies indicate depression rates can range from 25% to 44%, amplifying HIV transmission and increasing negative outcomes. In response to a high...

There’s a new tool to help prevent HIV in people who are at risk of contracting the virus, and health experts say it has the potential to change the trajectory of the global epidemic and may be especially beneficial for some older adults. In June, the U.S. Food and Drug...

Antimicrobial resistance is a significant global health challenge, particularly in low- and middle-income countries. In Malawi, frequent stockouts of essential medicines and the widespread dispensing of antibiotics without prescriptions have exacerbated the AMR burden, highlighting the urgent need for robust antimicrobial stewardship interventions. A study led by researchers at UNC...

SHEA, in partnership with ASGE, APIC, AAMI, AORN, HSPA, IDSA, SGNA, and The Joint Commission, developed this multisociety infection prevention guidance document for individuals and organizations that engage in sterilization or high-level disinfection (HLD). The supplementary material includes a summary of recommendations. The guidance provides an overview of the Spaulding...

Women recovering from preeclampsia with elevated vascular biomarkers have a higher risk of future cardiovascular diseases. Benjamin H. Chi, MD, MSc, investigated whether HIV on treatment was associated with biomarkers of cardiovascular risk in the weeks following delivery. Dr. Chi analyzed data from a six-month prospective cohort study conducted from...

Zika virus (ZIKV) caused unprecedented outbreaks in South America and the Caribbean in 2015–2016, leading primarily to a series of abnormalities in neonates termed congenital Zika syndrome. The threat of ZIKV reemergence has seen the development of multiple ZIKV vaccines that are at the preclinical stage or in early-stage clinical...