Tag: David Wohl

Chapel Hill, NC—A new study led by researchers at the Institute for Global Health and Infectious Diseases at the University of North Carolina School of Medicine in Chapel Hill shows an urgent need for improved detection and treatment of Lassa fever, published in The Lancet Infectious Diseases. Lassa fever–a severe...

The UNC School of Civic Life and Leadership’s Program for Public Discourse held the panel discussion “America’s Response to Covid” on Dec. 2. What can we learn from America’s response to the COVID-19 pandemic?  How should policymakers deal with future pandemics?  In a recent book co-authored with Stephen Macedo, Princeton...

Dr. David Alain Wohl is a professor of medicine in the Division of Infectious Diseases at the University of North Carolina (UNC) and the Institute of Global Health and Infectious Diseases. He is co-Principal Investigator of the Global UNC Infectious Diseases Clinical Research Unit and Site Leader of its Chapel...

“We at the Institute for Global Health and infectious diseases are a large community of multi-disciplinary investigators,” said Sonia Napravnik, PhD, in her webinar welcome message during University Research Week. “And essentially, we all focus on improving health globally and locally, here in North Carolina and across the US.” “Our...

Higher drug levels and combination therapy with low-dose oral methotrexate (LD-MTX) may reduce anti-tumor necrosis factor (TNF) treatment failure in pediatric Crohn’s disease. David Wohl, MD, conducted a post hoc analysis of the COMBINE trial, which compared anti-TNF monotherapy to combination therapy with LD-MTX. The study concluded that the LD-MTX...

North Carolina directly benefits from the work of global health researchers working in other countries, monitoring disease and containing outbreaks. For years, Fischer and David Wohl, MD, have contained diseases like Ebola virus, Marburg virus, Lassa virus, in West Africa, setting up field treatment units during outbreak settings to isolate and effectively care...

Global health issues may seem geographically distant, but they directly impact our local community through travel, immigration, emerging infectious diseases, and interconnected global economies. The ‘global’ in global health refers to the scope of problems, not just their location, which can be infectious diseases with pandemic potention. UNC’s global and...

ID Week took place October 16-19 in Los Angeles, CA, the joint annual meeting of the Infectious Diseases Society of America, the Society for Healthcare Epidemiology of America, the HIV Medicine Association, the Pediatric Infectious Diseases Society and the Society of Infectious Diseases Pharmacists. UNC’s Division of Infectious Diseases was...

March is Long COVID Awareness Month, marking four years since COVID-19 was declared a pandemic. But while much of society has moved on from masking, quarantining, and isolating, there are many who are managing health problems long after having COVID-19.  Researchers at the Institute for Global Health and Infectious Diseases are participating in the NIH...

In November 2020, Amy James Loftis was hyper-focused on keeping the Carolina community safe, building UNC’s COVID Surveillance Lab in three short months before the return of students. But there were many years leading up to that moment. Often described as the Institute’s secret weapon in the fight against global...

The UNC Institute for Global Health and Infectious Diseases is now enrolling participants in a fast-track trial of an oral COVID-19 treatment known as Bemnifosbuvir (BEM). Currently, Paxlovid is used for treating COVID-19. However, it is known to interact with common drugs that treat cholesterol, blood clots, and other conditions....

HIV virus eradication is a complex health challenge due to its long-lived persistence and how it hides in latently infected cells that escape the body’s immune system. Effective HIV treatments have decreased the likelihood of someone developing AIDS, while helping individuals live long and healthy lives without transmission to sexual...