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Effectiveness of Levonorgestrel Implant and Depot Medroxyprogesterone Acetate Injectable for Women living with HIV on Efavirenz

May 19, 2025
A collaborative study that included the Institute for Global Health and Infectious Diseases, UNC Project-Malawi, and the UNC Center For AIDS Research (CFAR), compared the contraceptive effectiveness of a typical-use LNG implant and depot medroxyprogesterone acetate (DMPA) injectable during efavirenz use. The study included women living with HIV (WLHIV) on...

Implications for Psychosocial Counseling Among People with HIV on Methadone Maintenance Treatment, Who Experience Common Mental Disorders in Vietnam

May 19, 2025
The psychological experiences and needs of people with human immunodeficiency virus (HIV), who use methadone maintenance treatment and have common mental disorders remain unknown in Hanoi, Vietnam. Due to limited services for common mental disorders, optimal delivery methods for psychotherapy are also unknown. Accordingly, a qualitative study led by Vivian Go,...

An Intervention to Support HIV Pre-Exposure Prophylaxis Care in Rural North Carolina

April 23, 2025
Pre-exposure prophylaxis (PrEP) is an important tool for reducing HIV incidence in the United States, but barriers to access, including race, sex, socioeconomic status, and geography, continue to persist. Sarah E. Rutstein, MD, PhD, Assistant Professor of Medicine, Christopher Hurt, MD, FIDSA, Professor of Medicine, and Brian Wells Pence, PhD, Professor of Epidemiology are conducting a study...

A Path for Scaling Mental Health Treatment in Low-Income Countries: Results from the SHARP Trial

April 2, 2024
Globally, mental health disorders rank as the greatest cause of disability and a leading contributor to the burden of disease. While the U.S. may struggle to meet the need for quality mental healthcare, treatment in most low- and middle-income (LMIC) countries – where 80% of those with mental illness live...

The Friendship Bench, Reimagining Mental Healthcare in Malawi

February 19, 2024
A new study published in Lancet-Global Health introduces the results of a five-year trial in Malawi that tested two implementation strategies for integrating mental health with general medical care. Led by UNC Institute for Global Health members Bradley Gaynes and Brian Pence, the study includes a cost-effectiveness analysis that will help inform scale-up decisions about...

Some of the Many Faces of HIV Research: Treatment, Prevention and Pursuing a Cure

December 13, 2022
HIV virus eradication is a complex health challenge due to its long-lived persistence and how it hides in latently infected cells that escape the body’s immune system. Effective HIV treatments have decreased the likelihood of someone developing AIDS, while helping individuals live long and healthy lives without transmission to sexual...