Yuri Fedoriw, MD
Director, Global Cancer Pathology, Institute for Global Health and Infectious Diseases
LabCorp Distinguished Professor, Vice Chair of Clinical Research and Academic Affairs, Department of Pathology and Laboratory Medicine
Co-Director, UNC Project Malawi Cancer Program
Areas of Interest
cancer genetics and pathology, HIV-associated lymphomas, cancer clinical trials in LMICs
About
Since 2011, Dr. Feoriw has been involved in the UNC Project-Malawi Cancer Program, developing and supporting diagnostic services in support of the Kamuzu Central Hospital Lymphoma Study, AIDS Malignancy Consortium, and NIH-funded clinical trials. He now serves as the co-director of the UNC Project-Malawi Cancer Program, the co-PI of the UNC-Malawi-South Africa Cancer Consortium (U54CA254564), and directs the translational lymphoma studies of samples submitted to UNC through this ongoing work. He has established weekly diagnostic telepathology conferences between Malawian pathologists and clinical teams to improve diagnostic accuracy and build regional capacity for cancer care. He supports training in global cancer research through the recently awarded Malawi Cancer Outcomes Research Program (D43CA260641 Fedoriw, MPI) that aims to develop global cancer research leaders in Malawi and UNC. Dr. Feoriw’s research interests focus on the immunologic and genetic mechanisms of lymphomagenesis, particularly in the setting of HIV infection. While hematologic malignancies and lymphoproliferative disorders (including Multicentric Castleman Disease) in sub-Saharan Africa arise under intrinsic and extrinsic pressures very different from those in the United States, comprehensive analyses of these diseases have not been performed. His laboratory group uses advanced sequencing, immunophenotypic, and cellular analyses to address gaps in our understanding of lymphomagenesis and tumor microenvironment in the context of HIV-associated immune dysregulation. Deciphering these tumor-host interactions is critical to better tailor treatment and improve outcomes, particularly in the era of cancer immunotherapy.
In the news
In the U.S., cancer diagnosis often involves costly biopsies and tests. In the south African country of Malawi, where the average annual income is around $300, patients can rarely afford such procedures — yet accurate diagnoses remain essential. To help, staff of the long-standing UNC Project Malawi Cancer Program are in the first phase of … Read more Cervical cancer is a preventable disease, yet one of the most common causes of death among women globally, despite screening measures proposed by the World Health Organization (WHO). In Malawi, efforts have focused on scaling up cervical cancer screening programs, as well as vaccination against the human papillomavirus (HPV). Still, the disease remains prevalent, with … Read more Dr. Bongani Kaimila of Lilongwe, Malawi, tragically and unexpectedly passed away at the age of 36 on November 4, 2022. The accident also claimed the life of his father. He is survived by his wife Eunice Kaimila, principal of the Adziwa Christian School, and their four young children. A GoFundMe account will help Bogani’s wife … Read more Global health research is a collaborative process, and each researcher at the Institute for Global Health & Infectious Diseases contributes a piece to solving the puzzle of disease and morbidity. With a new academic year underway, read what some of our investigators are working on to improve the health of global populations. Their multi-disciplinary findings will be … Read more
Malawi Cancer Program Develops Diagnostic Breakthrough
M-CORP Fellow Looks For Genetic Markers Associated With Cervical Cancer in Malawi Population
UNC Project Malawi and UNC Malawi Cancer Center Mourn the Loss of Bongani Kaimila–GoFundMe Account Will Support His Children.
IGHID Investigators Discuss Projects As New Academic Year Begins
Education
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Undergraduate
John Carroll University
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Medical School
Medical College of Ohio
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Residency
Yale School of Medicine
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Fellowship
Yale School of Medicine