Joseph J. Eron, MD
Co-Director, Clinical Trials Unit (CTU)
Director, CFAR Clinical Core
Chief, Division of Infectious Diseases
Herman and Louise Smith Distinguished Professor of Medicine
Areas of Interest
Antiretroviral therapy, resistance, pharmacology, transmission and HIV persistence and disruption of latency
About
Dr. Eron is Principal Investigator of the HIV/AIDS Clinical Research Unit at UNC-CH and Director of the Clinical Core for the UNC Center for AIDS Research (CFAR). He has been part of the AIDS Clinical Trials Group since 1993 and has held multiple leadership positions including Chair of the Optimization of ART Committee and the Cure Transformative Science Group. He is the Principal Investigator of the UNC Clinical trials Unit with sites in Chapel Hill, Greensboro, Lilongwe, Malawi and Hanoi, Vietnam. In addition, he is a leader of the UNC Acute HIV Infection research team and a collaborator in the UNC HIV Cure Center. Over the last 15 years, Dr. Eron has led the development of the UNC HIV CFAR clinic cohort that includes over 5,000 HIV infected individuals and has active collaboration and membership in the NA ACCORD and CNICS cohorts. Dr. Eron has over 400 publications in peer-reviewed journals focusing on antiretroviral therapy, resistance, pharmacology, transmission and HIV persistence, and disruption of latency. Recent work has included publications from the UNC-CFAR HIV Clinical Cohort, the ACTG, HPTN and IAS-USA HIV treatment guidelines in JAMA, 2020. Dr. Eron has worked extensively in the area of HIV drug development and led or participated in original studies of many antiretroviral therapies. He also continues as an active HIV infectious disease clinician. He is now the leader of the ACTG Scientific Agenda Steering Committee and is Vice Chair (co-PI) of the ACTG network.
In the news
Hospitalization causes among persons with HIV (PWH) have shifted to non-AIDS conditions, but the complete disease profile of hospitalized PWH has not been well described. To inform hospitalization and readmission prevention efforts, Thibaut Davy-Mendez, PhD, MSPH, Sonia Napravnik, PhD, and Joseph J. Eron, MD, examined non-AIDS disease prevalence among PWH hospitalized in 4 US cohorts and 1 Canadian … Read more As HIV care improves, people with Aids are now hospitalized more for non-AIDS conditions. Despite this, the complete disease profile of hospitalized people with HIV has not been well described. To inform hospitalization and readmission prevention efforts, researchers with the institute examined non-AIDS disease prevalence among PWH hospitalized in 4 US cohorts and 1 Canadian … Read more The ACTG (Advancing Clinical Therapeutics Globally, formerly the AIDS Clinical Trials Group) Network celebrates the A5321 trial, and a successful ten-year milestone this month. Joe Eron, MD, Chief of Infectious Diseases, is the ACTG Chair and leader of the ACTG Executive Committee. “The A5321 has been ongoing for 10 years and has contributed data to … Read more Investigators with the Institute for Global Health and Infectious Diseases (IGHID) participated in the 2025 Conference on Retroviruses and Opportunistic Infections (CROI) in San Francisco, California, March 9-12. Following are some highlights. In a CROI preview, Joe Eron, MD, was interviewed for the “Going Anti-Viral” IAS-USA podcast, discussing the state of HIV cure research … Read more
Changes in the Prevalence of Non-AIDS Conditions Among Hospitalized Persons With (HIV) in the United States and Canada, 2008–2018
Changes in the Prevalence of Non-AIDS Conditions Among Hospitalized Persons With Human Immunodeficiency Virus (HIV) in the United States and Canada, 2008–2018
Clinical Trials Unit Celebrates ACTG Milestone
IGHID Investigators Participate in CROI Conference
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Undergraduate
Harpur College
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Medical School
Harvard Medical School
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Residency
Massachusetts General Hospital, Harvard Medical School
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Fellowship
Massachusetts General Hospital, Harvard Medical School