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Parr, medical students conduct first study of tocilizumab in treating COVID-19

May 19, 2020
  In the first COVID-19 case series of tocilizumab in the United States, UNC-Chapel Hill researchers report sobering results. They say the drug should be used judiciously until randomized clinical trials determine tocilizumab’s true efficacy. Meanwhile, medical students sidelined from clinical rotations by the virus conducted the research with lightning...

‘Landmark’ study finds long-acting injectable drug highly effective in preventing HIV

May 18, 2020
  Large-scale study funded by NIAID and ViiV Healthcare halted early after cabotegravir, dosed every two months, shows higher efficacy than daily oral pill.   The decades-long search for a vaccine to prevent HIV reached a new milestone as results from HPTN 083, a global large-scale study, show that the...

Study finds three strains of resistant bacteria, identifying greater diversity

May 14, 2020
    A new study by the Multi-Drug-Resistant Organism Network of the Antibacterial Resistance Leadership Group (ARLG) has found that strains of carbapenem-resistant enterobacterales (CRE), a major threat to vulnerable patient populations, are more diverse than previously thought. The MDRO Network is led by UNC Infectious Diseases investigator David van...

Comprehensive primary care clinic proposed for people living with HIV

May 6, 2020
A novel collaboration between UNC’s Department of Medicine and Division of Infectious Diseases includes creating a multidisciplinary primary care clinic to serve people living with HIV. The new model lays the groundwork for multidisciplinary care in advance of the move to Eastowne. Led by Claire Farel MD, MPH, medical director of the...

Boyce, Aiello team with state, local agencies to study COVID-19 cases with mild or no symptoms

May 6, 2020
Ross Boyce, MD, MSc, assistant professor of medicine in the infectious diseases division, and, Allison Aiello, PhD, MS, professor of epidemiology at the UNC Gillings School of Global Public Health, are leading a study along with Aaron Fleischauer, PhD, MSPH, at NC Department of Health and Human Services and other...

Cohen, Fowler inducted into UNC’s Order of the Golden Fleece

May 6, 2020
Myron Cohen, MD, Yeargan-Bate Distinguished Professor of medicine, microbiology, and immunology and epidemiology and director of the Institute for Global Health and Infectious Diseases, and Wesley Fowler, MD, associate dean for medical alumni affairs and professor of obstetrics and gynecology,and have been inducted into the Order of the Golden Fleece,...

Schranz receives NIH grant to study patient care for drug-use related heart infections

May 6, 2020
Asher Schranz, MD, MPH, assistant professor of medicine in the division of infectious diseases, has received a grant from the NIH National Institute on Drug Abuse for the project “Drug-use associated infective endocarditis: Post-hospitalization outcomes and patient treatment preferences.” Schranz’s research is broadly focused on the intersection of infectious diseases...

Pay-it-forward model increases STI testing and community health

April 27, 2020
Watch animation video explaining UNC Project-China’s STI pay-it-forward study. Gonorrhea and chlamydia are two common sexually transmitted infections (STIs) that increase HIV risk among many key populations, including gay and bisexual men. But most men are not tested for STIs, in part because of the cost and low community engagement....

Study addresses COVID-19 infection rates for household members

April 24, 2020
By Alyssa LaFaro As seven states now require masks and face coverings for visiting essential businesses or using public transportation, it seems like those spaces are where we are most at risk for COVID-19 infection. But, in truth, the riskiest place could be our homes — at least, if you live with someone...

She’s raising funds to feed coworkers on frontlines of Covid-19

April 17, 2020
Kathy James was watching the evening news a week or so ago when she saw a story about people in Winston-Salem who were organizing to bring food to local hospital staff fighting Covid-19. We need to do something like that for our people, she thought. James is an administrative coordinator...

From our director: Building national model for crisis response, management

April 9, 2020
  By Myron Cohen, MD Our UNC infectious diseases community, encompassing many disciplines, has responded remarkably to COVID-19. Our physicians have been deployed to patient care and to advise the University and health system’s leadership. Researchers are quickly pivoting their work to focus on COVID. Among the many who have...

‘A global effort’: Report from Malawi

April 7, 2020
Irving Hoffman, international director of the Institute’s UNC Project-Malawi, offers this report as the country recorded its first death from COVID-19. As of April 8, 2020, despite limited testing, Malawi has recorded 10 COVID-19 cases with one death and some evidence of community spread. UNC Project-Malawi is taking a leading...

Faculty affiliates turn focus to COVID-19 treatments, prevention research

April 6, 2020
  Researchers within UNC’s School of Medicine are working tirelessly to provide knowledge to impact the current COVID-19 pandemic and future pandemics. “UNC SOM is home to many world-renowned experts on infectious disease and virology,” says Blossom Damania, Boshamer Distinguished Professor and Vice Dean for Research at the UNC School...

Report from China: Linghua Li, MD, PhD, shares COVID-19 observations

March 21, 2020
Linghua Li, MD, PhD, is an infectious disease specialist and AIDS clinic director at Eighth People’s Hospital in Guangzhou, China. She did two years of postdoctoral training in infectious diseases at Duke University and at UNC, working with the Institute’s David Wohl, MD. Here, she reports from the frontlines on dealing with COVID-19 in Guangzhou, which...

Grant boosts antimicrobial resistance efforts in Malawi

February 18, 2020
The Institute for Global Health and Infectious Diseases and UNC Project-Malawi were awarded a $4.5 million grant by the UK’s Fleming Fund to strengthen Malawi’s One Health Antimicrobial Resistance (AMR) program.  The grant will support the national AMR coordination committee and technical working groups, supporting ownership and alignment and scaling up a One Health AMR...

Researchers reverse HIV latency

February 11, 2020
Overcoming HIV latency – induction of HIV in CD4+ T cells that lay dormant throughout the body – is a major step toward creating a cure for HIV. For the first time, scientists at UNC-Chapel Hill, Emory University, and Qura Therapeutics – a partnership between UNC and ViiV Healthcare –...

Partnership with Nicaragua expands with addition of PhD program

February 6, 2020
UNC has expanded its partnership with the Universidad Nacional Autónoma de Nicaragua-León, or UNAN, which since 2003 has encompassed the exchange of research, faculty, and clinical learners, to now include the development of a PhD program housed at UNAN. The program, which offers a PhD in biomedical sciences with mention...

Pediatric lab opens in Malawi’s Kamuzu Central Hospital

November 15, 2019
Kamuzu Central Hospital in Lilongwe, Malawi, celebrated the opening of its pediatric laboratory with a November 14, 2019 ceremony. The collaborative project was led by Elizabeth Fitzgerald, MD, a pediatric emergency medicine specialist, with support from UNC Project-Malawi and funding from the Malawi Children’s Initiative. Rob Krysiak, MS, co-director of...

Researchers receive up to $10.7 million to study chlamydia vaccine

May 30, 2019
  Chlamydia is the most prevalent bacterial sexually transmitted infection (STI) in the world. There is no vaccine to prevent infection. However, researchers from the University of North Carolina at Chapel Hill, in partnership with colleagues at other sites in the U.S., Europe and Australia, will receive up to $10.7...

Team lands $14M to improve pregnancy outcomes

May 15, 2019
A team led by Jeff Stringer, MD, associate director of research for the Institute for Global Health & Infectious Diseases, has received $14 million from the Bill & Melinda Gates Foundation to conduct two studies aimed at improving pregnancy outcomes in the world’s poorest countries. The interdisciplinary group from departments...