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Extranodal Natural Killer/T-cell Lymphoma in Malawi

September 6, 2017

September 2017- Our experience with these patients highlights that ENKTCL does indeed occur in SSA, increases familiarity with ENKTCL among clinicians and pathologists throughout the region, and emphasizes the need for better diagnosis and treatment for this neglected population.

Salvage Chemotherapy for Adults with Relapsed or Refractory Lymphoma

August 20, 2017

August 2017 – Lymphoma is highly associated with HIV in sub-Saharan Africa and contributes to worse outcomes relative to resource-rich settings. This study describes 21 patients with relapse or refractory lymphoma who were prospectively treated with salvage chemotherapy in Malawi.

Cancer Trials in sub-Saharan Africa

July 1, 2017

July 2017- Dr. Gopal proposes a potential resource-tailored framework for cancer clinical trials and for aligning care and research in SSA.

Beyond Endemic Burkitt Lymphoma: Navigating Challenges of Differentiating Childhood Lymphoma Diagnoses Amid Limitations in Pathology Resources in Lilongwe, Malawi

June 24, 2017

June 2017 Abstract Background.  Although Burkitt lymphoma (BL) is the most common childhood lymphoma in sub-Saharan Africa, Hodgkin lymphoma (HL) and other non-Hodgkin lymphomas occur. Diagnosing non-jaw mass presentations is challenging with limited pathology resources. Procedure.  We retrospectively analyzed 114 pediatric lymphomas in Lilongwe, Malawi, from December 2011 to June 2013 and compared clinical versus … Read more

International Cancer Seminars: Esophageal Squamous Cell Carcinoma

June 22, 2017

June 2017 – An international workshop aimed at examining the state of current science regarding esophageal squamous cell carcinoma. These discussions highlight a series of difficult questions which are recommended to inform and prioritize future research efforts. 

Navigating Challenges of Differentiating Childhood Lymphoma Diagnoses Amid Limited Pathology Resources in Malawi

June 16, 2017

June 2017 – Although Burkitt lymphoma (BL) is the most common childhood lymphoma in sub-Saharan Africa, Hodgkin lymphoma (HL) and other non-Hodgkin lymphomas occur. We found that lymphomas other than Burkitt accounted for 35% of childhood lymphoma diagnoses. Although over-reliance on clinical diagnosis for BL was a limitation, confidence in non-BL diagnoses improved with time … Read more

Risk Factors for Common Cancers at Kamuzu Central Hospital in Malawi

June 14, 2017

June 2017 – In light of limited data regarding risk factors for different cancers in Malawi, we assessed risk factors for and epidemiologic patterns of common cancers among patients treated at Kamuzu Central Hospital. We found that age, smoking, and HIV are important risk factors for the 3 commonest cancer types (oesophageal, KS, and cervical), … Read more

Breast Cancer Knowledge, Behaviors, and Preferences in Malawi

May 8, 2017

April, 2017 – Breast cancer is very common in Sub-Sahara Africa, but many misconceptions about it make early detections and treatment difficult. This study looks at what misconceptions exist and what barriers need to be addressed.

Epstein-Barr virus DNA for pediatric Burkitt lymphoma diagnosis

April 3, 2017

March 2017 – Diagnosing pediatric Burkitt Lymphoma in sub-Saharan Africa is difficult, as many tools are currently not available. This study found that measuring Epstein-Barr virus DNA could help with setting the diagnosis, prognosis, and predicting the response.