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Epidemiological and Histopathological Profile of Malignant Melanoma in Malawi

April 10, 2019

April 2019 – Studies on malignant melanoma have largely focused on Caucasian populations with very limited data on the disease in black Africans. This retrospective study characterizes melanoma cases in Lilongwe, Malawi and demonstrates that malignant melanoma occurs in black Malawians and may be an under-appreciated malignancy.

Prospective Study of Burkitt Lymphoma Treatment in Adolescents and Adults in Malawi

February 11, 2019

February 2019 – Although Burkitt lymphoma (BL) is common in sub-Saharan Africa (SSA) and highly curable in high-income countries, there are few prospective nonpediatric BL studies from SSA and no regional standard of care. This study represents one of the best characterized prospective cohorts of nonpediatric BL in SSA.

Rosai-Dorfman Disease in Malawi

December 11, 2018

December 2018 – We present the case report of an HIV‐negative female adolescent with Rosai-Dorfman disease, a rare lymphoproliferative disease with limited cases reported in sub‐Saharan Africa.

Mature Outcomes and Prognostic Indices in DLBCL in Malawi

December 11, 2018

December 2018- Outcomes for diffuse large B-cell lymphoma (DLBCL) in sub-Saharan Africa are poorly described. We report mature data from one of the first prospective SSA cohorts and propose a setting-appropriate prognostic model.

High Cancer Burden Among ART Users in Malawi

December 6, 2018

December 2018- In sub-Saharan Africa, limited epidemiological data describe cancer burden among ART users. We link cases from the population-based cancer registry with EMRs supporting ART delivery in Malawi’s two largest HIV cohorts, Lighthouse Trust and Queen Elizabeth Central Hospital to identify cancer burden.

HIV-Associated Multicentric Castleman Disease In Malawi

November 26, 2018

November 2018-  Despite high burden of Kaposi sarcoma and HIV, multicentric Castleman disease is rarely reported in SSA. To supplement previous reports on MCD cases in Malawi, we describe a larger cohort of MCD patients with longer follow-up.

Ending Tribalism in Global Oncology

October 20, 2018

October 2018- Dr. Satish Gopal urges the global health community to prioritize meaningful multilateral partnerships in order to improve the coordination of patient care and research.

‘Discovering’ primary effusion lymphoma in Malawi

October 1, 2018

September 2018- Although HIV and HHV8 are highly prevalent in SSA, there are scarce reports of primary effusion lymphoma (PEL) from the region, likely reflecting underdiagnosis. This article describes the two recently confirmed cases of extracavitary PEL in Malawi.  

Treating Burkitt Lymphoma in Children and AYA in Sub-Saharan Africa

July 19, 2018

July 2018- Although highly effective, high-intensity cytotoxic treatments for Burkitt lymphoma are available in resource-rich settings, these therapies are usually not feasible in SSA, and lower-intensity continuous infusion approaches are impractical. We review current treatment approaches in SSA and discuss options for risk stratification and individualize therapy.