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HIV-Associated Multicentric Castleman Disease In Malawi

November 26, 2018

November 2018-  Despite high burden of Kaposi sarcoma and HIV, multicentric Castleman disease is rarely reported in SSA. To supplement previous reports on MCD cases in Malawi, we describe a larger cohort of MCD patients with longer follow-up.

Ending Tribalism in Global Oncology

October 20, 2018

October 2018- Dr. Satish Gopal urges the global health community to prioritize meaningful multilateral partnerships in order to improve the coordination of patient care and research.

‘Discovering’ primary effusion lymphoma in Malawi

October 1, 2018

September 2018- Although HIV and HHV8 are highly prevalent in SSA, there are scarce reports of primary effusion lymphoma (PEL) from the region, likely reflecting underdiagnosis. This article describes the two recently confirmed cases of extracavitary PEL in Malawi.  

Treating Burkitt Lymphoma in Children and AYA in Sub-Saharan Africa

July 19, 2018

July 2018- Although highly effective, high-intensity cytotoxic treatments for Burkitt lymphoma are available in resource-rich settings, these therapies are usually not feasible in SSA, and lower-intensity continuous infusion approaches are impractical. We review current treatment approaches in SSA and discuss options for risk stratification and individualize therapy.

Plasmablastic lymphoma in Malawi

June 29, 2018

June 2018- Despite high prevalence of HIV in SSA, descriptions of Plasmablastic lymphoma (PBL) are scare.  In one of the first clinical descriptions of PBL, we report on characteristics, treatment, and outcomes of 12 pathologically confirmed PBL cases in Lilongwe.

Dissecting Heterogeneous Outcomes for Paediatric Burkitt Lymphoma in Malawi after Anthracycline-Based Treatment

June 15, 2018

June 2018 – We discuss our experience in relation to others’ major contributions to paediatric Burkitt lymphoma care in sub-Saharan Africa. We believe that sharing of heterogeneous regional experience is valuable for rigorous examination, and look forward to on-going collaborative efforts to define best approaches for this disease, which we are actively pursuing with many … Continued

Frequent HIV and Young Age Among Individuals With Diverse Cancers

June 8, 2018

June 2018- We report the epidemiology of patients with cancer recorded by a hospital-based cancer registry at Kamuzu Central Hospital, the sole provider of comprehensive oncology services for half the country and location of a high-volume pathology laboratory.

Guidelines for sub-Saharan Africa: a Call for Evidence

April 11, 2018

April 2018- Cancer care in resource-limited settings is radically different from cancer care in resource-rich settings. Drs. Painschab and Gopal comment on the urgent need for region-specific data and clinical trials to address the rising cancer burden in SSA.