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Case Report: Multicentric Castleman Disease as a Manifestation of Immune Reconstitution Inflammatory Syndrome in Malawi

October 11, 2023

December 2022 INTRODUCTION Multicentric Castleman disease (MCD) is a lymphoproliferative disorder characterized by systemic inflammation, lymphadenopathy, and cytopenias. MCD caused by Kaposi sarcoma herpesvirus (MCD-KSHV) frequently arises in the context of HIV. It can be associated with immune reconstitution inflammatory syndrome (IRIS), but MCD-IRIS is rarely reported in sub-Saharan Africa (SSA) where HIV and KSHV … Read more