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Introductory Workshop on Chichewa Language and Malawi Culture

March 7, 2022

Implementation and Evaluation of Educational Videos to Improve Cancer Knowledge and Patient Empowerment

February 22, 2022
February 17 2022 PURPOSE Low health literacy is a leading cause of treatment abandonment among patients receiving cancer care at Kamuzu Central Hospital (KCH) in Malawi. METHODS We developed cancer educational videos featuring Malawian providers and played them in the KCH oncology clinic. The videos addressed cancer-related topics, including disease...

Kaimila Launches Study to Determine Feasibility of Endoscopic Screening for Esophageal Cancer in Malawi

February 22, 2022
UNC Project Malawi Cancer Program esophageal cancer and cancer clinic division lead Bongani Kaimila, MBBS, MSc, launched a cross-sectional study to determine the feasibility of endoscopic screening for Esophageal Squamous Cell Carcinoma (ESCC) precursor lesions in Malawi and the relationship with poor oral health. In Malawi, ESCC is the third...

UNC School of Nursing Professor Helps Build Oncology Nursing Capacity in Malawi

February 21, 2022
UNC Lineberger Comprehensive Cancer Center has appointed Ashley Leak Bryant, PhD, RN, OCN, FAAN, as assistant director of Cancer Research Training Education Coordination (CRTEC). Bryant joins Bernard Weissman, PhD, and Jen Jen Yeh, MD, co-associate directors of CRTEC. The goal of CRTEC is to develop the next generation of cancer...

UNC Awarded NCI Grant to Strengthen Institutional Capacity for Cancer Research in Malawi

September 23, 2021
University of North Carolina at Chapel Hill was one of four institutions to be awarded a National Cancer Institute D43 grant to strengthen institutional capacity for cancer research in LMIC’s. The 5-year grant strengthens the partnership of the UNC Institute for Global Health and Infectious Diseases and the UNC Lineberger...

Improving Access to Self-Expanding Metal Stents for Patients With Esophageal Cancer in Eastern Africa: A Stepwise Implementation Strategy

September 23, 2021
January 2021-The eastern corridor of Africa is affected by a high burden of esophageal cancer (EC), with > 90% of patients presenting with advanced disease. Self-expanding metal stents (SEMS) have been previously reported as safe and effective for palliation of malignant dysphagia in resource-limited settings; however, access is limited throughout...

Safety and efficacy of rituximab in patients with diffuse large B-cell lymphoma in Malawi: a prospective, single-arm, non-randomised phase 1/2 clinical trial

September 23, 2021
July 2021- There are no clinical trials involving patients with diffuse large B-cell lymphoma (DLBCL) in sub-Saharan Africa since antiretroviral therapy (ART) for HIV became widely available in this region. We aimed to establish the safety and efficacy of rituximab plus cyclophosphamide, doxorubicin, vincristine, and prednisone (R-CHOP) in patients with...

Comparison of best supportive care, CHOP, or R-CHOP for treatment of diffuse large B-cell lymphoma in Malawi: a cost-effectiveness analysis

September 23, 2021
July 2021- Cost-effectiveness data for cancer treatment are needed from sub-Saharan Africa, where diffuse large B-cell lymphoma (DLBCL) is a common, curable cancer. In high-income countries, the standard of care for DLBCL is R-CHOP (rituximab, cyclophosphamide, doxorubicin, vincristine, and prednisone) chemoimmunotherapy. Rituximab is often not available in sub-Saharan Africa due...

Feasibility of upfront mobile money transfers for transportation reimbursement to promote retention among patients receiving lymphoma treatment in Malawi

September 23, 2021
May 2021-Cancer outcomes in sub-Saharan Africa (SSA) remain suboptimal, in part due to poor patient retention. Many patients travel long distances to receive care, and transportation costs are often prohibitively expensive. These are well-known and established causes of delayed treatment and care abandonment in Malawi and across SSA. We sent...

Pediatric lymphoma patients in Malawi present with poor health-related quality of life at diagnosis and improve throughout treatment and follow-up across all Pediatric PROMIS-25 domains

September 23, 2021
August 2021- Patient-reported outcomes (PROs) that assess health-related quality of life (HRQoL) are increasingly important components of cancer care and research that are infrequently used in sub-Saharan Africa (SSA). We administered the Chichewa Pediatric Patient-Reported Outcome Measurement Information System Pediatric (PROMIS)-25 at diagnosis, active treatment, and follow-up among pediatric lymphoma...