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Years: 2019-2020

Training Site: UNC Project-Malawi

Country: Malawi

Mentors: Katherine Hoadley, PhD; Satish Gopal, MD, MPH; Yuri Fedoriw, MD, PhD

Title: “Gene Expression Profiling of Primary Breast Tumors in Malawian Women”

Program Objectives:

Hypothesis 1: Breast cancer in adult Malawian women exhibit gene expression profiles that more often characterize aggressive breast cancer subtypes similar to African Americans and different from White Americans.

Aim 1: Evaluate gene expression profiles and molecular subtypes in Malawian breast cancer patients.

Hypothesis 2: Breast cancer in adult Malawian women exhibit unique pathways that are enriched in each cancer subtype.

Aim 2: Enhance Malawi laboratory capacity for future breast cancer genomic studies.

NIH Support: Fogarty fellow postdoctoral training award, NCI supplement

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