Training Site: UNC Project-Malawi
Mentors: Katherine Hoadley, PhD; Satish Gopal, MD, MPH; Yuri Fedoriw, MD, PhD
Title: “Gene Expression Profiling of Primary Breast Tumors in Malawian Women”
Hypothesis 1: Breast cancer in adult Malawian women exhibit gene expression profiles that more often characterize aggressive breast cancer subtypes similar to African Americans and different from White Americans.
Aim 1: Evaluate gene expression profiles and molecular subtypes in Malawian breast cancer patients.
Hypothesis 2: Breast cancer in adult Malawian women exhibit unique pathways that are enriched in each cancer subtype.
Aim 2: Enhance Malawi laboratory capacity for future breast cancer genomic studies.
NIH Support: Fogarty fellow postdoctoral training award, NCI supplement