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Years: 2019-2020

Training Site: Makerere University Lung Institute at Mulago Hospital

Country: Uganda

Mentors: William Checkley, MD, PhD; Bruce Kirenga, MD

Title: “Interstitial Lung Disease (ILD) in Uganda: An epidemiologic survey and risk factor analysis”

Program Objectives: The goal is to examine the prevalence and risk factors for interstitial lung disease (ILD) among urban and rural populations in Uganda. The proposed project will investigate the association of ILD with other environmental and infectious exposures. This will be the first such investigation in Sub-Saharan Africa and will provide epidemiologic data about ILD and identify associated exposures, both domestic and occupational.

Aim 1: Identify the prevalence and risk factors (occupations, biomass fuel smoke exposure, tobacco use, infections, urbanization) for ILD in an urban and rural cohort of adults Uganda.

Aim 2: Define sub-types of ILD based upon radiographic examination in a cohort of patients with restrictive lung disease in Uganda.

Aim 3: Examine the co-incidence of infectious diseases (HIV and TB) among participants with ILD, including evaluation of TB treatment history, HIV viral load and CD4 count for sub-group analysis.

NIH Support: Fogarty fellow postdoctoral training award

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