Training Years: 2016-2017
Training Site: University of Ghana Medical School
Mentor: Michael D. Wilson, PhD; Jonathon Stiles, PhD
Title: Saliva-Based Diagnostic for Testing, Treating, and Tracking (T3) Malaria
Project Objectives: The main hypothesis of this study is that Plasmodium secretes antigens that induce host biomarkers that can be detected in saliva at limits lower than that for blood.
Aim 1: To determine the proteome profile and abundance of Plasmodium antigens in saliva of asymptomatic and symptomatic subjects and compare with levels in blood.
Aim 2: To assess levels of select host and Plasmodium antigens secreted in saliva of asymptomatic and symptomatic subjects and compare with levels in blood.
NIH Support: Fogarty fellowship postdoctoral training award