Category: HIV/AIDS and STIs

Antiretroviral therapy (ART) for viral suppression in people living with HIV (PWH) improves life expectancy and interrupts transmission. And new long-acting ART injectables have become a convenient treatment, helping overcome the burden of pills and the stigma associated with taking daily medication. But while there has been a 68% reduction...

Briefly summarize your background and interests, and how you came to the Institute. I originally trained as a biomedical engineer and gained experience with in-host modeling of influenza during my Master’s degree at the University of Virginia. I was interested in continuing to work on infectious disease modeling, but wanted...

UNC at the STI & HIV 2025 World Congress in Montreal UNC Chapel Hill was well represented at the STI & HIV 2025 World Congress. Centered on the theme “Sexual Health for All,” the congress took place in Montreal, Canada, from July 27 to 30, 2025. This biannual congress, organized by...

Dr. Edward Browne, associate professor of medicine leading the Browne Lab within the HIV CURE Center, focuses on developing methods for studying and eliminating the latent HIV reservoir from infected patients. Latently infected cells are resistant to current HIV therapies and can persist in infected patients for decades. He recently...

HIV cure strategies that aim to induce viral reactivation for immune clearance leverage latency reversal agents to modulate host pathways, which directly or indirectly facilitate viral reactivation. Inhibition of BET (bromo and extra-terminal domain) family member BRD4 reverses HIV latency, but enthusiasm for the use of BET inhibitors in HIV...

Syphilis vaccine development remains a high priority with a rising number of congenital syphilis cases worldwide. Unfortunately, vaccine development is still in a pre-clinical phase, and ongoing translational work is needed to identify vaccine candidates targeting highly conserved surface-exposed antigens expressed by geographically diverse strains of Treponema pallidum (TPA). But...

UNC Eshelman School of Pharmacy Dean Angela Kashuba, Pharm.D., a member of the Institute for Global Health and Infectious Disease, was selected for the 2024 Carolina Alumni Faculty Service Award. Established in 1990, the award “honors faculty members who have performed outstanding service for the University or the alumni association.” ...

April is sexually transmitted infections (STI) awareness month, and Arlene Seña, MD, MPH, a researcher with the Institute for Global Health and Infectious Diseases, is sounding the alarm about the importance of syphilis prevention, testing, and treatment. U.S. syphilis cases have increased nearly 80% since 2018,  a level not seen...

Hard-won gains in the long-running global HIV epidemic are in danger of being lost, argues Wafaa El-Sadr, MD, MPH, MPA, global director of ICAP at Columbia University, in a new commentary published today in Science. Co-authored with Myron S. Cohen, MD, director of the Institute for Global Health and Infectious...

Led by Mina Hosseinipour, MD, MPH, the NIH’s National Institute of Child Health and Human Development (NICHD), has funded the project “Preventing Infant Infections with Implementation Science in Malawi.” (PRI3SM). The program, in partnership with the Republic of Malawi’s Ministry of Health, comprises three studies to address gaps in prevention services,...

Researchers at the UNC School of Medicine’s International Center for the Advancement of Translational Science and the Institute for Global Health and Infectious Diseases have developed a new approach for the detailed evaluation of HIV infection throughout the entire male genital tract, HIV acquisition via the penis and the efficient...

Research capacity building is intrinsic to the work of the Institute for Global Health & Infectious Diseases (IGHID), nurturing trainees here and around the world. Eli Arant, MD, a third-year infectious diseases fellow in the T-32 training program, represents this training at its best, moving the literature forward in an...