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Mixing of Tecovirimat in Water to Support Oral Dosing of Infants and Children With Mpox

April 28, 2025
Following the 2022 mpox outbreak, dozens of cases occurred in young children within the U.S., and thousands have occurred internationally, where the Clade I virus has disproportionately affected young children in the Democratic Republic of Congo and surrounding areas.This is particularly concerning as increased severity of disease, mortality, and rates...

Reducing Global Inequities in Access to Medical Oxygen

April 28, 2025
Tisungane Mvalo, MD, is an Associate Professor of Pediatrics at UNC as well as the in-country Pediatric Director of UNC Project Malawi. He practices clinically at Kamuzu Central Hospital in Lilongwe, Malawi. In a recent article in The Lancet Global Health, Dr. Mvalo discusses the issues with access to medical...

Transmission Models of Respiratory Infections in Carceral Settings

April 23, 2025
David L. Rosen, MD, PhD, MSPH, an Associate Professor of Infectious Diseases, says prevention and control of infectious disease outbreaks in carceral settings face unique challenges in a paper published in Science Direct. Transmission modeling is a powerful tool for understanding and addressing these challenges, but reviews of modeling work in...

Tackling Tuberculosis By Leveraging Nutritional Rehabilitation and Tuberculosis Programs

April 23, 2025
Tisungane Mvalo, MD, an Associate Professor of Pediatrics and the in-country Pediatric Director of UNC Project-Malawi, authored a new paper published in The Lancet Child Adolescent Health about children with severe acute malnutrition who have a high but underappreciated risk of tuberculosis. Severe acute malnutrition affects more than 13 million children younger...

Breast Cancer Treatment Patterns and Guidelines, Concordant Treatment Among Malawian Women

April 23, 2025
Dr. Jennifer Morgan, under the mentorship of Dr. Katie Reeder Hayes, Associate Professor of Oncology and Dr. Tamiwe Tomoka, UNC Project-Malawi Cancer Program Co-Director, describes breast cancer treatment patterns by stage and curative-intent guideline-concordant treatment (GCT) receipt among Malawian women in BMC Women’s Health. A prospective cohort of breast cancer patients was enrolled...

An Intervention to Support HIV Pre-Exposure Prophylaxis Care in Rural North Carolina

April 23, 2025
Pre-exposure prophylaxis (PrEP) is an important tool for reducing HIV incidence in the United States, but barriers to access, including race, sex, socioeconomic status, and geography, continue to persist. Sarah E. Rutstein, MD, PhD, Assistant Professor of Medicine, Christopher Hurt, MD, FIDSA, Professor of Medicine, and Brian Wells Pence, PhD, Professor of Epidemiology are conducting a study...

Associations Between Internalized HIV Stigma and Cognitive Function Among Older Women with HIV

April 23, 2025
Monica Maria Diaz, MD, MS, an assistant professor of neurology, published a study in the Journal of Gerontology measuring internalized HIV stigma in the Women’s Interagency HIV Study between 2013 and 2015. Internalized HIV stigma refers to the negative beliefs, feelings, and attitudes that people with HIV (PWH) adopt about themselves...

Incidence of Statin Initiation Among People With and Without Human Immunodeficiency Virus

April 23, 2025
To reduce atherosclerotic cardiovascular disease (ASCVD) among people living in the US with human immunodeficiency virus (HIV, PLWH), it is critical to asess shortfalls in statin initiation. Stephen R. Cole, PhD, Myron S. Cohen, MD, Joseph J. Eron, MD, and Michelle Floris-Moore, MD, MS., aimed to describe patterns in clinically indicated...

An Examination of Multiple Illnesses and Social Related Stressors During the COVID-19 Pandemic

April 22, 2025
Joanna “Asia” Maselko, ScD, Associate Professor in the Department of Epidemiology, is working to improve preparation for future pandemics by examining the myriad psychosocial pathways through which the COVID-19 pandemic impacted mental health. In a recent article in BMC Public Health, they present findings on two less documented pathways: (a) COVID...

Association of Long COVID-19 Symptoms, Physical Function, and Activities of Daily Living Among Older Women

April 22, 2025
Emily W. Gower, PhD, is an associate professor at the Gillings School of Global Public Health working in ocular epidemiology. Her primary area of research interest is in improving trichiasis surgery outcomes for individuals with trachoma, which is the leading infectious cause of blindness worldwide. She has led multiple clinical...

Clinical Trials Unit Celebrates ACTG Milestone

April 7, 2025
The ACTG (Advancing Clinical Therapeutics Globally, formerly the AIDS Clinical Trials Group) Network celebrates the A5321 trial, and a successful ten-year milestone this month. Joe Eron, MD, Chief of Infectious Diseases, is the ACTG Chair and leader of the ACTG Executive Committee. “The A5321 has been ongoing for 10 years...

Grant Submission Updates

April 7, 2025
Greetings from the Pre-Award team! If you are planning to submit a grant application, please let us know at least 1 month in advance (preferably 2 months), so that we have time to meet our internal deadlines: Reminders: Most NIH funded research now requires a Data Management Plan.  UNC’s Research...