Klebsiella pneumoniae is an opportunistic pathogen and a leading cause of healthcare-associated infections in hospitals, which are frequently antimicrobial resistant (AMR). Exacerbating the public health threat posed by K. pneumoniae, some strains also harbour additional hypervirulence determinants.
Virginia Miller, PhD, is investigating the genetic diversity, evolution, mobilisation, and prevalence of rmpADC in a dataset of 14,000 genomes from isolates of the Klebsiella pneumoniae species complex, and describes the RmST virulence typing scheme for tracking rmpADC variants for the purposes of genomic surveillance.