Pain self-management (PSM) interventions are low-risk, effective interventions for chronic pain that have high potential for scalability. Economic evaluations are a key component of assessing scalability. Claire Farel, MD, MPH, an Assistant Professor of Infectious Diseases in the Department of Medicine, and Sonia Napravnik, PhD, an Associate Professor of Medicine in the Division of Infectious Diseases evaluated the cost-effectiveness of a tailored PSM called Skills to Manage Pain (STOMP) as compared to enhanced usual care (EUC) among people with HIV (PWH) and chronic pain.